The PD1 antibody (biotin) from MyBioSource.com is a Rat Monoclonal antibody. The PD1 antibody (biotin) has been validated for the following applications: Flow Cytometry.
Description
Rat monoclonal PD1 antibody (biotin)
The RMP1-30 antibody reacts with mouse PD-1, a 55 kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 and PD-L2. Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. RMP1-30 does not block the binding of either B7-H1-Ig or B7-DC-Ig to PD-1 transfectants